Professor Nicholas A. Peppas Gives Lecture at “Master Forum” and Appointed as Honorary Professor

2017-04-27

On the afternoon of April 21, 2017, at the invitation of President Xuetao Cao, Professor Nicholas A. Peppas of the University of Texas at Austin, member of National Academy of Engineering and National Academy of Medicine, visited CAMS&PUMC, gave a lecture at “Master Forum”, and was appointed as honorary professor. President Xuetao Cao chaired the academic activity, and more than 230 relevant scientific researchers, teachers and students attended this activity.




At the Master Forum, President Xuetao Cao first introduced the educational background and scientific research achievements of Professor Nicholas A. Peppas. Professor Peppas is an internationally renowned expert in the field of biomaterial and drug delivery system, and has made important contributions to the development of the global biomedical engineering field. He has published more than 1,400 papers, cited for more than 94,000 times. He has written 37 monographs and coauthored books, and obtained 48 patents.


Subsequently, Professor Peppas gave an academic presentation entitled “Multiresponsive Nanogels for the Delivery of Small Interfering RNA and Advanced Protein Therapeutic Agents for Treatment of Autoimmune Diseases”. He started with his original intention and motivation for scientific researches in the field of biomedical engineering, and gave a detailed introduction to the latest achievements of drug delivery methods and biological materials that he studied and designed. The equation calculated by Professor Peppas based on Fickian and non-Fickian diffusion properties of drugs, proteins, and polypeptides has become the standardized method for analyzing pharmaceutical formulations and systems, and been known as “Peppas equation”. In addition, he applied Transmucosal nanoparticles and Tranferrin in delivering such proteins as in oral insulin, and provided the possibility for research and development of oral insulin; this protein delivery system could also be used in the treatment of rheumatic arthritis, osteoporosis, macular degeneration and other diseases. As small interfering RNA (siRNA) became a popular research of new drug development since the Nobel Prize in 2006, Professor Peppas combined siRNA wrapped by micron paste at the outer layer and siRNA wrapped by nano paste at the inner layer to develop the oral delivery system for siRNA, and applied it in treating the inflammatory bowel disease.




Professor Peppas’ wonderful lecture won warm applauses from teachers and students present at the activity. His enthusiasm for scientific research and persistence in scientific transformation motivated them. Finally, he gave detailed and wonderful answers to relevant questions from teachers and students on the spot.

 

(Text/Department of International Cooperation, Photo/News Center)